PB17-026-01

CAT: 0804-HY-157318Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-157318Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PB17-026-01 is a potent SHP2 allosteric inhibitor and shows the highest inhibitory activity with an IC50 value of 38.9 nM. PB17-026-01 can be used for the research of tumor[1].
UNSPSC
12352005
Target
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pb17-026-01.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)C(N(CC2)CCC32[C@@H](N)[C@@H](C)OC3)=NN4C1=C(C5=CC=CC(Cl)=C5Cl)C=C4
Molecular Formula
C22H25Cl2N5O2
Molecular Weight
462.37
References & Citations
[1]Luo Y, et al. Discovery of the SHP2 allosteric inhibitor 2- ((3R,4R) -4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl) -5- (2,3-dichlorophenyl) -3-methylpyrrolo[2,1-f][1,2,4] triazin-4 (3H) -one. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :398-404.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P990602IMA-026
HY-169264SJYHJ-026
HY-174850CFON-026
HY-122209DVR-01
HY-137464A-01OATD-01
HY-161768VCC972839:01
HY-106839NKS-01
HY-155870DL-01
HY-P991492-01RSM-01
HY-156214-01NICE-01

Alternative Products

CatalogName
MF-0116283-01PB17-026-01
M39424-01KD-026
MBS5776303AGI-026
MF-0110436-01SJYHJ-026
MF-0118348-01CFON-026
NBP2-90309-100ulRabbit Monoclonal PIG3 Antibody (026)
C00690-01Anti-IL-13 (IMA-026)
NBP2-90189-100ulRabbit Monoclonal CCDC134 Antibody (026)
NBP2-89326-100ulRabbit Monoclonal EphB6 Antibody (026)
T3640COS-7-DRA1*01:01/DRB1*01:01 Cell Line

Popular Products