WML-01

• Description :

  WML-01 is a fungicide with EC50s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum, F. fujikuroi and S. sclerotiorum. WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) (HY-N6684) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic[1].

• UNSPSC :

  12352005

• Target :

  Fungal

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  CC1=C(C(OC12CCCCC2)=O)/C(C)=C3SC(NC/3=O)=S

• Molecular Formula :

  C15H17NO3S2

• Molecular Weight :

  323.43

• References & Citations :

  [1]Li Y, et al. Discovery of WML-01, a Spirocyclic Butenolide Derivative Featuring a Rhodanine Motif, Exhibiting High Fungicidal Activity against Fusarium Species. J Agric Food Chem. 2025 Oct 15;73 (41) :25805-25812.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3057478-36-8]