DVR-01

• Description :

  DVR-01 is a HBV inhibitor with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.403-3.273 μM. DVR-01 can be used for the research of HBV infection and related diseases[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  HBV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/dvr-01.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCC1=CC=CC=C1)C2=CC=C(C(S(N3CCCCCC3)(=O)=O)=C2)Cl

• Molecular Formula :

  C20H23ClN2O3S

• Molecular Weight :

  406.93

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]Campagna MR, et al. Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids. J Virol. 2013 Jun;87 (12) :6931-42.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [330461-34-2]