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MAGL-IN-9

CAT: 0804-HY-157040Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157040Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAGL-IN-9 (compound 16) is a selective and reversible MAGL inhibitor with IC50 2.7 nM[1].
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/magl-in-9.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(CC2=CC=C(F)C(SC3=NC=CC(C(F)(F)F)=C3)=C2)CC1)C4=CC=CC(O)=C4
Molecular Formula
C25H22F4N2O2S
Molecular Weight
490.51
References & Citations
[1]Di Stefano M, et al. Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors[J]. European Journal of Medicinal Chemistry, 2023: 115916.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported