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MAGL-IN-222

CAT: 0931-T206357-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206357-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
877804-65-4
Target
Lipase
Related Pathways
Metabolism
Bioactivity
MAGL-IN-222 (Compound ZQ-7) is a covalent inhibitor that targets monoacylglycerol lipase (MAGL), with an IC50 of 42.31 μM. It reduces the breakdown of 2-arachidonoylglycerol (2-AG), enhancing intracellular 2-AG levels, thereby inhibiting the proliferation and migration of MDA-MB-231 breast cancer cells. MAGL-IN-222 is applicable in breast cancer research and related diseases.
Smiles
N#CC=1C(=O)N(C(=O)C(=CC2=CC=C(C=C2)N(CC)CC)C1C)C3CCS(=O)(=O)C3
Molecular Formula
C22H25N3O4S
Molecular Weight
427.517
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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