Cbl-b-IN-7

Cbl-b-IN-7

• CAS Number: 2815221-35-1
• UNSPSC Description: Cbl-b-IN-7 (Compound 248) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.7 nM and 5.2 nM, respectively[1].
• Target Antigen: E1/E2/E3 Enzyme
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cbl-b-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: F[C@@H](C1=NN=CN1C)C2(C3=CC(N4CC5=C(C(F)(F)F)C=C([C@H](C)NC6(CCC6)C)C=C5C4=O)=CC=C3)COC2
• Molecular Weight: 557.58
• References & Citations: [1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported