Cbl-b-IN-7

• Description :

  Cbl-b-IN-7 (Compound 248) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.7 nM and 5.2 nM, respectively[1].

• UNSPSC :

  12352005

• Target :

  E1/E2/E3 Enzyme

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cbl-b-in-7.html

• Solubility :

  10 mM in DMSO

• Smiles :

  F[C@@H](C1=NN=CN1C)C2(C3=CC(N4CC5=C(C(F)(F)F)C=C([C@H](C)NC6(CCC6)C)C=C5C4=O)=CC=C3)COC2

• Molecular Formula :

  C29H31F4N5O2

• Molecular Weight :

  557.58

• References & Citations :

  [1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2815221-35-1]