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DGKα-IN-8

CAT: 0804-HY-156578Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156578Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DGKα-IN-8 (Example 51) is a DGKα inhibitor (IC50=22.491 nM; EC50=0.256 nM) . DGKα-IN-8 can be used to study cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection[1].
CAS Number
2886717-70-8
UNSPSC
12352005
Target
DGK; HIV
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/dgkα-in-8.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(N(CC(F)F)C2=NC3=C(C4=C2C=CC(Cl)=C4)N(C)N=N3)=CC(C#CC(C)(C)O)=C1
Molecular Formula
C23H19ClF3N5O
Molecular Weight
473.88
References & Citations
[1]Julian A Codelli, et al. Diacylglyercol kinase modulating compounds. Patent WO2022271659A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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