PROTAC BRD4 Degrader-21

• CAS Number:

  2503036-46-0

• UNSPSC Description:

  PROTAC BRD4 Degrader-21 (Comp 74) is a PROTAC degrader of BRD4. PROTAC BRD4 Degrader-21 displays significant tumor growth inhibition in tumor -bearing xenograft models in mice and can be used for anticancer research[1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-brd4-degrader-21.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(N4CCC(CC4)CN5CCN(CC5)CC6=CC=C(N7C(C8=CC(C(C)C)=C(C=C8O)O)=NNC7=O)C=C6)=O)C9=NN=C(C)N29.Cl

• Molecular Weight:

  925.97

• References & Citations:

  [1]Weiwen Ying, et.al. Methods and compositions for targeted protein degradation

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported