PROTAC BRD4 Degrader-21

PROTAC BRD4 Degrader-21

• CAS Number: 2503036-46-0
• UNSPSC Description: PROTAC BRD4 Degrader-21 (Comp 74) is a PROTAC degrader of BRD4. PROTAC BRD4 Degrader-21 displays significant tumor growth inhibition in tumor -bearing xenograft models in mice and can be used for anticancer research[1].
• Target Antigen: Epigenetic Reader Domain; PROTACs
• Type: Reference compound
• Related Pathways: Epigenetics;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-brd4-degrader-21.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(N4CCC(CC4)CN5CCN(CC5)CC6=CC=C(N7C(C8=CC(C(C)C)=C(C=C8O)O)=NNC7=O)C=C6)=O)C9=NN=C(C)N29.Cl
• Molecular Weight: 925.97
• References & Citations: [1]Weiwen Ying, et.al. Methods and compositions for targeted protein degradation
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported