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DHFR-IN-10

CAT: 0804-HY-156412Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156412Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DHFR-IN-10 (compound 4c) is a potent DHFR inhibitor, with an IC50 of 4.21 μM for M. tuberculosis DHFR enzyme. DHFR-IN-10 exhibits potent antituberculosis efficiency[1].
CAS Number
929484-47-9
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dhfr-in-10.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC=C(C2=CSC(N3N=C(C4=CC=CS4)CC3C5=CC=CS5)=N2)C=C1
Molecular Formula
C20H14BrN3S3
Molecular Weight
472.44
References & Citations
[1]Dawood DH, et, al. New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies. ACS Omega. 2023 Oct 13;8 (42) :39250-39268.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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