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CES2A-IN-1

CAT: 0804-HY-155755Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155755Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CES2A-IN-1 (compound 20w) is a potent CES2A inhibitor with an IC50 value of 1.6 nM for human CES2A. CES2A-IN-1, a bysspectin A derivative, shows an approximately 1000-fold improvement over the lead compound bysspectin A[1].
UNSPSC
12352005
Target
Carboxylesterase (CES) ; Drug Derivative
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hces2a-in-1.html
Solubility
10 mM in DMSO
Smiles
CCCCCCC(C1=C2C=C(C3=CC(OC)=CC=C3O)OC2=CC=C1C)=O
Molecular Formula
C23H26O4
Molecular Weight
366.45
References & Citations
[1]Li W, et al. New bysspectin A derivatives as potent inhibitors of human carboxylesterase 2A. Eur J Med Chem. 2023 Nov 5;259:115708.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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