CES2A-IN-1

• Description:

  CES2A-IN-1 (compound 20w) is a potent CES2A inhibitor with an IC50 value of 1.6 nM for human CES2A. CES2A-IN-1, a bysspectin A derivative, shows an approximately 1000-fold improvement over the lead compound bysspectin A[1].

• UNSPSC:

  12352005

• Target:

  Carboxylesterase (CES) ; Drug Derivative

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hces2a-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCC(C1=C2C=C(C3=CC(OC)=CC=C3O)OC2=CC=C1C)=O

• Molecular Formula:

  C23H26O4

• Molecular Weight:

  366.45

• References & Citations:

  [1]Li W, et al. New bysspectin A derivatives as potent inhibitors of human carboxylesterase 2A. Eur J Med Chem. 2023 Nov 5;259:115708.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported