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DprE1-IN-7

CAT: 0804-HY-155512Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155512Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DprE1-IN-7 (Compound 64) is a DprE1 inhibitor. DprE1-IN-7 has anti-TB activity against Mtb H37Rv strain (MIC: 1 μM) . DprE1-IN-7 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-7 has high microsomal stability and medium clearance[1].
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dpre1-in-7.html
Solubility
10 mM in DMSO
Smiles
NC1=NC(N2CCOCC2)=NC3=C1N(CC4=CC=C5C=CC=CC5=C4)C=N3
Molecular Formula
C20H20N6O
Molecular Weight
360.41
References & Citations
[1]Finger V, et al. 2,6-Disubstituted 7- (naphthalen-2-ylmethyl) -7H-purines as a new class of potent antitubercular agents inhibiting DprE1. Eur J Med Chem. 2023 Oct 5;258:115611.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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