BT-PROTAC

• Description :

  BT-PROTAC is a bioorthogonally activatable prodrug. BT-PROTAC can accurately control the activity of PROTAC[1].

• UNSPSC :

  12352005

• Target :

  PROTACs

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/bt-protac.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H](NC(COCCOCCOCCNC(C[C@H]1C2=NN=C(N2C3=C(C(C4=CC=C(C=C4)Cl)=N1)C(C)=C(C)S3)C)=O)=O)C(C)(C)C)N5[C@@H](C[C@H](C5)OC(OC6CCCCC/C=C/6)=O)C(N[C@H](C7=CC=C(C=C7)C8=C(N=CS8)C)C)=O

• Molecular Formula :

  C59H74ClN9O10S2

• Molecular Weight :

  1168.86

• References & Citations :

  [1]Bi T, et al. Rational Design of Bioorthogonally Activatable PROTAC for Tumor-Targeted Protein Degradation. J Med Chem. 2023 Oct 23.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3032848-64-6]