BT-Amide

• Target :

  PYK2

• Related Pathways :

  Tyrosine Kinase/Adaptors

• Bioactivity :

  BT-Amide is an orally active Pyk2 kinase (Pyk2kinase) inhibitor with an IC50 of 44.69 nM. It prevents glucocorticoid-induced bone loss and demonstrates bone-protective activity in C57BL/6 mice.

• Smiles :

  CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)NC(=O)CCCCC(=O)NCCCC(O)(P(=O)(O)O)P(=O)(O)O)OC

• Molecular Formula :

  C29H38ClN7O11P2

• Molecular Weight :

  758.053

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C