BT-114143

• Description:

  BT-114143 is a plasminogen activation inhibitor, with an IC50 of 8.42 μM. BT-114143 can be used in the research of hemorrhagic diseases caused by hyperfibrinolysis, such as traumatic bleeding, severe menstrual bleeding, postpartum hemorrhage, and complications of hemophilia[1].

• UNSPSC:

  12352005

• Target:

  PAI-1

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=P (O) (C1=CC=C (CNCC2) C2=N1) O

• Molecular Formula:

  C8H11N2O3P

• Molecular Weight:

  214.16

• References & Citations:

  [1]Ji S, et al. Discovery of BT-114143, a Novel and Potent Phosphoric Acid-Containing Small-Molecule Plasminogen Activation Inhibitor for Hyperfibrinolysis. J Med Chem. 2025 Mar 27;68 (6) :6084-6099.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2796343-04-7