BT-114143

• Description :

  BT-114143 is a plasminogen activation inhibitor, with an IC50 of 8.42 μM. BT-114143 can be used in the research of hemorrhagic diseases caused by hyperfibrinolysis, such as traumatic bleeding, severe menstrual bleeding, postpartum hemorrhage, and complications of hemophilia[1].

• CAS Number :

  [2796343-04-7]

• UNSPSC :

  12352005

• Target :

  PAI-1

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=P(O)(C1=CC=C(CNCC2)C2=N1)O

• Molecular Formula :

  C8H11N2O3P

• Molecular Weight :

  214.16

• References & Citations :

  [1]Ji S, et al. Discovery of BT-114143, a Novel and Potent Phosphoric Acid-Containing Small-Molecule Plasminogen Activation Inhibitor for Hyperfibrinolysis. J Med Chem. 2025 Mar 27;68 (6) :6084-6099.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported