Ara-SH

CAT: 0804-HY-154971Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-154971Size:1 Each
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Description
Ara-SH is a Cytarabine mercaptopropionic acid-substituted derivative. Ara-SH is used as the trigger to fabricate a smart Cytarabine and Venetoclax-coloaded nanoparticle (AV-NP) through self-assembly. Ara-SH exhibits remarkable synergistic antileukemia effects in vitro and in vivo[1].
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ara-sh.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NC(N([C@@H]2O[C@@H]([C@H]([C@@H]2O)O)CO)C=C1)=O)CCS
Molecular Formula
C12H17N3O6S
Molecular Weight
331.34
References & Citations
[1]Lejiao Jia, et al. Smart and Generalizable Cytarabine Derivative-Triggered Nanoparticles for Synergistic Therapy of Relapsed/Refractory Acute Myeloid Leukemia. ACS Appl Mater Interfaces. 2023 Jun 14;15 (23) :27624-27637.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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