Ara-SH

• UNSPSC Description:

  Ara-SH is a Cytarabine mercaptopropionic acid-substituted derivative. Ara-SH is used as the trigger to fabricate a smart Cytarabine and Venetoclax-coloaded nanoparticle (AV-NP) through self-assembly. Ara-SH exhibits remarkable synergistic antileukemia effects in vitro and in vivo[1].

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ara-sh.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=NC(N([C@@H]2O[C@@H]([C@H]([C@@H]2O)O)CO)C=C1)=O)CCS

• Molecular Weight:

  331.34

• References & Citations:

  [1]Lejiao Jia, et al. Smart and Generalizable Cytarabine Derivative-Triggered Nanoparticles for Synergistic Therapy of Relapsed/Refractory Acute Myeloid Leukemia. ACS Appl Mater Interfaces. 2023 Jun 14;15(23):27624-27637.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported