Ara-ATP

• Description :

  Ara-ATP, a structural analog of ATP, inhibits poly (A) polymerase activity by competing with ATP[1].

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/ara-atp.html

• Solubility :

  10 mM in DMSO

• Smiles :

  NC1=C2N=CN([C@@H]3O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)[C@@H]3O)C2=NC=N1

• Molecular Formula :

  C10H16N5O13P3

• Molecular Weight :

  507.18

• References & Citations :

  [1]Ghoshal K, Jacob ST. Ara-ATP impairs 3'-end processing of pre-mRNAs by inhibiting both cleavage and polyadenylation. Nucleic Acids Res. 1991 Nov 11;19 (21) :5871-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3714-60-1]