Ara-ATP

• UNSPSC Description:

  Ara-ATP, a structural analog of ATP, inhibits poly(A) polymerase activity by competing with ATP[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ara-atp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=C2N=CN([C@@H]3O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)[C@@H]3O)C2=NC=N1

• Molecular Weight:

  507.18

• References & Citations:

  [1]Ghoshal K, Jacob ST. Ara-ATP impairs 3'-end processing of pre-mRNAs by inhibiting both cleavage and polyadenylation. Nucleic Acids Res. 1991 Nov 11;19(21):5871-5.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3714-60-1