Ara-UTP
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Ara-UTP
Description:
Ara-UTP is a sugar-modified nucleotide triphosphate that deceives RNA polymerases and blocks chain extension.Product Name Alternative:
Ara-uridine triphosphateUNSPSC:
12352005Target:
DNA/RNA SynthesisRelated Pathways:
Cell Cycle/DNA DamageField of Research:
OthersSmiles:
O=C(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)NC1=OMolecular Formula:
C9H15N2O15P3Molecular Weight:
484.14References & Citations:
[1]Yuan C, Goonetilleke EC, Unarta IC, Huang X. Incorporation efficiency and inhibition mechanism of 2'-substituted nucleotide analogs against SARS-CoV-2 RNA-dependent RNA polymerase. Phys Chem Chem Phys. 2021 Sep 22;23 (36) :20117-20128. doi: 10.1039/d1cp03049c. PMID: 34514487.Shipping Conditions:
Room temperatureScientific Category:
Reference compound1Clinical Information:
No Development ReportedCAS Number:
[60102-52-5]
