Ara-UTP

• Description :

  Ara-UTP is a sugar-modified nucleotide triphosphate that deceives RNA polymerases and blocks chain extension.

• Product Name Alternative :

  Ara-uridine triphosphate

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Others

• Smiles :

  O=C(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)NC1=O

• Molecular Formula :

  C9H15N2O15P3

• Molecular Weight :

  484.14

• References & Citations :

  [1]Yuan C, Goonetilleke EC, Unarta IC, Huang X. Incorporation efficiency and inhibition mechanism of 2'-substituted nucleotide analogs against SARS-CoV-2 RNA-dependent RNA polymerase. Phys Chem Chem Phys. 2021 Sep 22;23 (36) :20117-20128. doi: 10.1039/d1cp03049c. PMID: 34514487.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [60102-52-5]