PPARγ agonist 8

CAT: 0804-HY-153982Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-153982Size:1 Each
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Description
PPARγ agonist 8 is an agonist of PPARγ. PPARγ agonist 8 induces peroxisome proliferator response element (PPRE) -luciferase activity with an EC50 of 0.2 μM[1].
CAS Number
[1049800-41-0]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparγ-agonist-8.html
Solubility
10 mM in DMSO
Smiles
OC(CC1=C/C(C2=CC=C(F)C=C21)=C\C3=CC=C(C=C3)SC(F)(F)F)=O
Molecular Formula
C19H12F4O2S
Molecular Weight
380.36
References & Citations
[1]Felts AS, et.al. Sulindac derivatives that activate the peroxisome proliferator-activated receptor gamma but lack cyclooxygenase inhibition. J Med Chem. 2008 Aug 28;51 (16) :4911-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ

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