PPARγ agonist 8

• Description :

  PPARγ agonist 8 is an agonist of PPARγ. PPARγ agonist 8 induces peroxisome proliferator response element (PPRE) -luciferase activity with an EC50 of 0.2 μM[1].

• UNSPSC :

  12352005

• Target :

  PPAR

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/pparγ-agonist-8.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(CC1=C/C(C2=CC=C(F)C=C21)=C\C3=CC=C(C=C3)SC(F)(F)F)=O

• Molecular Formula :

  C19H12F4O2S

• Molecular Weight :

  380.36

• References & Citations :

  [1]Felts AS, et.al. Sulindac derivatives that activate the peroxisome proliferator-activated receptor gamma but lack cyclooxygenase inhibition. J Med Chem. 2008 Aug 28;51 (16) :4911-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PPARγ

• CAS Number :

  [1049800-41-0]