PF-06478939 (TFA)

PF-06478939 (TFA)

• UNSPSC Description: PF-06478939 TFA is a non-brain-penetrating peptide that is an agonist at oxytocin (OT) receptor and vasopressin receptor with EC50 values of 0.01 nM and 0.078 nM, respectively[1].
• Target Antigen: Oxytocin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/pf-06478939-tfa.html
• Solubility: 10 mM in DMSO
• Smiles: OC1=CC=C(C[C@@H](C(N[C@@H]([C@H](CC)C)C(N[C@H](C(N[C@H]2CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](N)CSSC[C@@H](C(N3CCC[C@H]3C(N[C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCCCCCCCCCCCC)=O)=O)C(NCC(N)=O)=O)=O)=O)NC2=O)=O)C=C1.O=C(O)C(F)(F)F.[x]
• References & Citations: [1]Modi ME, et al. Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing. J Pharmacol Exp Ther. 2016 Aug;358(2):164-72.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported