PF-06655075 (TFA)

• Description :

  PF-06655075 (TFA) is the TFA form of PF-06655075 (HY-153963) . PF-06655075 is a novel andnon–brain-penetrant oxytocin receptor agonist with increased selectivity for the oxytocin receptor and significantly increased pharmacokinetic stability. PF-06655075 can be used as a tool compound to further explore the role of peripheral oxytocin in behavioral response[1].

• UNSPSC :

  12352209

• Target :

  Oxytocin Receptor

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/pf-06655075-tfa.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC1=CC=C(C[C@@H](C(N[C@@H]([C@H](CC)C)C(N[C@H](C(N[C@H]2CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](N)CSSC[C@@H](C(NCC(N[C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCCCCCCCCCCCC)=O)=O)C(NCC(N)=O)=O)=O)=O)NC2=O)=O)C=C1.O=C(O)C(F)(F)F.[x]

• Molecular Formula :

  C75H130N14O22S2.xC2HF3O2

• References & Citations :

  [1]Meera E, et al. Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing. J Pharmacol Exp Ther. 2016 Aug; 358 (2) : 164–172.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported