PF-06478939

CAT: 0804-HY-153964Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-153964Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PF-06478939 is a non-brain-penetrating peptide that is an agonist at oxytocin (OT) receptor and vasopressin receptor with EC50 values of 0.01 nM and 0.078 nM, respectively[1].

UNSPSC

12352005

Target

Oxytocin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pf-06478939.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C(C[C@@H](C(N[C@@H]([C@H](CC)C)C(N[C@H](C(N[C@H]2CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](N)CSSC[C@@H](C(N3CCC[C@H]3C(N[C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCCCCCCCCCCCC)=O)=O)C(NCC(N)=O)=O)=O)=O)NC2=O)=O)C=C1

Molecular Formula

C78H134N14O22S2

Molecular Weight

1684.11

References & Citations

[1]Modi ME, et al. Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing. J Pharmacol Exp Ther. 2016 Aug;358 (2) :164-72.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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T79173-01	PF-06478939
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MBS579460	PF-03084014 (PF-3084014)
M36412-01	PF-17
M34376-01	PF-184298
M33060-01	PF-04957325
M28021-01	PF-1355
M26783-01	PF-04937319
M26368-01	PF-04885614
M24156-01	PF-9363

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