PROTAC SOS1 degrader-4

• UNSPSC Description:

  PROTAC SOS1 degrader-4 (compound 10) is a potent SOS1 degrader. PROTAC SOS1 degrader-4 shows antiproliferative activity[1].

• Target Antigen:

  PROTACs; Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;MAPK/ERK Pathway;PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-sos1-degrader-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCN(CC2CCC3(CCN(C(C4=CC=C(Cl)C(N5CCC(NC5=O)=O)=C4)=O)CC3)CC2)CC1)[C@H]6CC[C@H](C7=CC8=C(N[C@H](C)C9=CC=CC%10=C9CCS%10(=O)=O)N=C(C)N=C8C=C7OC)CC6

• Molecular Weight:

  993.65

• References & Citations:

  [1]ZhengQing Ye, et al. Sos1 degrading agent and preparation method therefor and application thereof. WO2022223033A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported