PROTAC SOS1 degrader-4

PROTAC SOS1 degrader-4

• UNSPSC Description: PROTAC SOS1 degrader-4 (compound 10) is a potent SOS1 degrader. PROTAC SOS1 degrader-4 shows antiproliferative activity[1].
• Target Antigen: PROTACs; Ras
• Type: Reference compound
• Related Pathways: GPCR/G Protein;MAPK/ERK Pathway;PROTAC
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-sos1-degrader-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1CCN(CC2CCC3(CCN(C(C4=CC=C(Cl)C(N5CCC(NC5=O)=O)=C4)=O)CC3)CC2)CC1)[C@H]6CC[C@H](C7=CC8=C(N[C@H](C)C9=CC=CC%10=C9CCS%10(=O)=O)N=C(C)N=C8C=C7OC)CC6
• Molecular Weight: 993.65
• References & Citations: [1]ZhengQing Ye, et al. Sos1 degrading agent and preparation method therefor and application thereof. WO2022223033A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported