ADN 138

CAT: 0804-HY-113738Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-113738Size:1 Each
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Description
ADN-138 is an aldose reductase inhibitor. ADN-138 reduces sorbitol levels in diabetic nerves and results in significant increases in MNCV and Na+, K+-ATPase in the nerves. ADN-138 can be used in the research of diabetic nerve complications[1].
CAS Number
[99434-90-9]
UNSPSC
12352005
Target
Aldose Reductase; Endogenous Metabolite; Na+/K+ ATPase
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Neurological Disease
Smiles
O=C(N1)C2(CC1=O)C3=C4N(CCOC4=CC(Cl)=C3)C2=O
Molecular Formula
C13H9ClN2O4
Molecular Weight
292.67
References & Citations
[1]Hirata Y, Okada K. Relation of Na+, K (+) -ATPase to delayed motor nerve conduction velocity: effect of aldose reductase inhibitor, ADN-138, on Na+, K (+) -ATPase activity. Metabolism. 1990 Jun;39 (6) :563-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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