RegisterLogin

GXF-111

CAT: 0804-HY-153414Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-153414Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
GXF-111, a PROTAC molecule, can promote selective degradation of cellular BRD3 and BRD4-L. GXF-111 has binding affinities for BRD3 BD1 and BRD3 BD2 with Ki values of 11.97 nM and 2.35 nM, respectively. GXF-111 can be used for the research of cancer[1].
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gxf-111.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2C(NC(CC2)=O)=O)CC3=C1C=CC=C3CCCCNCC4=CC=C(C5=CC=C6C(C(NC7=CC=C(Cl)C=C7)CCC8=NN=C(C)N86)=C5)C=C4
Molecular Formula
C42H42ClN7O3
Molecular Weight
728.28
References & Citations
[1]Yan Z, et al. Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines. Eur J Med Chem. 2023;254:115381.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-120943-01K-111
HY-100450-01BML-111
HY-116730CHS-111
HY-100418-01SKA-111
HY-168111BNZ-111
HY-156920VDX-111
HY-P11259UPG-111
HY-P991524MM-111
HY-P991660ARGX-111
HY-W898997CRBN ligand-111

Alternative Products

CatalogName
MBS5820695GXF-111
166340RTI-111
T9901A-1616-01MM-111
T24799-01SKA-111
T22526-01BML-111
T87611-01VDX-111
110080Hsp-111
T200718-01BNZ-111
BUP02766-01K-111
ABC-TC0462J-111

Popular Products