Products for Research Use Only
RegisterLogin

PCC0105005

CAT: 0013-GTR19274385-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19274385-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PCC0105005 is a dual-target CGRP Receptor antagonist (IC50 = 1.01 nM) and 5-HT1F Receptor partial agonist (EC50 = 77.91 nM) . It demonstrates significant efficacy in rat models of migraine. PCC0105005 significantly reduces the expression of CGRP and c-Fos proteins while inhibiting the phosphorylation levels of ERK and CREB. This compound is useful for migraine research.
CAS Number
2921670-99-5
Smiles
N (C (=O) C=1C=C2C (=CC1) NC (=O) C (=C2) C3CCN (C (N[C@H] (CC=4C=C5C (=C (C) C4) NN=C5) C (=O) N6CCN (CC6) C7CCN (C) CC7) =O) CC3) C=8C=C9C (=CNC9=CC8) C%10CCN (C) CC%10
Molecular Formula
C51H63N11O4
Molecular Weight
894.14
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19238225-01PCC0105003

Alternative Products

CatalogName
HY-179684PCC0105005

Popular Products