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Lp-PLA2-IN-12

CAT: 0804-HY-153183Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153183Size:1 Each
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Description
Lp-PLA2-IN-12 (compound 19) is an Lp-PLA2 inhibitor. Lp-PLA2-IN-12 can be used for the study of neurodegenerative related diseases such as Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), or cardiovascular disease including atherosclerosis[1].
CAS Number
2637485-14-2
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lp-pla2-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C[C@]3(CC[C@H]4CCC3)N4C2=CC(OCC(C=C5F)=CC(F)=C5OC(C=N6)=CN=C6C)=N1
Molecular Formula
C24H23F2N5O3
Molecular Weight
467.47
References & Citations
[1]Xiao Qiong, et al. Tetracyclic pyrimidinone compounds, preparation method, composition and application thereof. Patent, CN112574221A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported