Lp-PLA2-IN-9

• Description:

  Lp-PLA2-IN-9 (compound 17), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.1 for rhLp-PLA2. Lp-PLA2-IN-9 has the potential for neurodegenerative related diseases research[1].

• UNSPSC:

  12352005

• Target:

  Phospholipase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/lp-pla2-in-9.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N=C(C=C2N1CC34N2C(CC4)CC3)OCC5=CC(F)=C(C(F)=C5)OC6=CC=C(C(Cl)=C6)OC(F)(F)F

• Molecular Formula:

  C25H19ClF5N3O4

• Molecular Weight:

  555.88

• References & Citations:

  [1]Qiong Xiao, et al. Tetracyclic pyrimidinone compounds, preparation method, composition and application thereof. CN112574221B.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2637485-12-0]