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Lp-PLA2-IN-6

CAT: 0804-HY-142774Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142774Size:1 Each
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Description
Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has the potential for neurodegenerative related diseases research[1].
CAS Number
2637485-13-1
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lp-pla2-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(C=C2N1CC34N2C(CC4)CCC3)OCC5=CC(F)=C(C(F)=C5)OC6=CC(C(F)(F)F)=NC=C6
Molecular Formula
C25H21F5N4O3
Molecular Weight
520.45
References & Citations
[1]Qiong Xiao, et al. Tetracyclic pyrimidinone compounds, preparation method, composition and application thereof. CN112574221B.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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