Urease-IN-5

• Description:

  Urease-IN-5 is an inhibitor of urease with an IC50 value of 1.473 µM. Urease-IN-5 has low cytotoxicity and inhibitory activity on P. vulgaris with an IC50 value of 17.78 µg/mL[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/urease-in-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCN1C (SC (C1=O) CC (NCC2=CC=CC=C2) =O) =O

• Molecular Formula:

  C16H20N2O3S

• Molecular Weight:

  320.41

• References & Citations:

  [1]Dastyafteh N, et al. New thioxothiazolidinyl-acetamides derivatives as potent urease inhibitors: design, synthesis, in vitro inhibition, and molecular dynamic simulation. Sci Rep. 2023 Jan 2;13 (1) :21.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported