Urease-IN-3

• Description:

  Urease-IN-3 (Compound L12) is a potent inhibitor of Urease with an IC50 of 1.449 μM. Urease-IN-3 is a flavonoid analogue compound[1].

• UNSPSC:

  12352005

• Target:

  Bacterial; Urease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/urease-in-3.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N/N=C/C1=C(O)C=CC2=C1OC(C3=CC=C(F)C=C3)=CC2=O)C4=CC=CC=C4

• Molecular Formula:

  C23H15FN2O4

• Molecular Weight:

  402.37

• References & Citations:

  [1]Liu H, et al. Flavonoid analogues as urease inhibitors: Synthesis, biological evaluation, molecular docking studies and in-silico ADME evaluation. Bioorg Chem. 2020;105:104370.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2543651-72-3]