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Urease-IN-8

CAT: 0804-HY-155973Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155973Size:1 Each
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Description
Urease-IN-8 (Compound 5e) is a competitive Urease inhibitor (IC50: 3.51 μM, Ki: 3.11 μM) . Urease-IN-8 can be used for research of peptic and gastric ulcers[1].
CAS Number
517906-16-0
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/urease-in-8.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)C2=NN=C3SCC(C4=CC=C(C5=CC=CC=C5)C=C4)=NN23
Molecular Formula
C23H18N4OS
Molecular Weight
398.48
References & Citations
[1]Jalal Uddin, et al. Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment. ACS Omega 2023, 8, 35, 31890?1898.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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