Urease-IN-8

• Description:

  Urease-IN-8 (Compound 5e) is a competitive Urease inhibitor (IC50: 3.51 μM, Ki: 3.11 μM) . Urease-IN-8 can be used for research of peptic and gastric ulcers[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/urease-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC=C(C=C1)C2=NN=C3SCC(C4=CC=C(C5=CC=CC=C5)C=C4)=NN23

• Molecular Formula:

  C23H18N4OS

• Molecular Weight:

  398.48

• References & Citations:

  [1]Jalal Uddin, et al. Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment. ACS Omega 2023, 8, 35, 31890?1898.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [517906-16-0]