YEATS4 binder-1

• UNSPSC Description:

  YEATS4 binder-1(4e) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a Ki value of 37 nM[1].

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/yeats4-binder-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CN2C(C=C1)=C([C@@H]3[C@@H](C)CN(CC4(O)CCOCC4)CC3)C(C)=N2)NCC

• Molecular Weight:

  414.54

• References & Citations:

  [1]Allyn T Londregan, et al. Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4. J Med Chem. 2023 Jan 12;66(1):460-472.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported