YEATS4 binder-1

YEATS4 binder-1

• UNSPSC Description: YEATS4 binder-1(4e) is a potent and selective YEATS4 binder that binds to the KAc recognition site of the YEATS structural domain with a Ki value of 37 nM[1].
• Target Antigen: Histone Methyltransferase
• Type: Reference compound
• Related Pathways: Epigenetics
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/yeats4-binder-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CN2C(C=C1)=C([C@@H]3[C@@H](C)CN(CC4(O)CCOCC4)CC3)C(C)=N2)NCC
• Molecular Weight: 414.54
• References & Citations: [1]Allyn T Londregan, et al. Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4. J Med Chem. 2023 Jan 12;66(1):460-472.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported