JAK2 JH2 binder-1
CAT:
804-HY-146186-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JAK2 JH2 binder-1
- CAS Number: 2923309-41-3
- UNSPSC Description: JAK2 JH2 binder-1 (compound 11) is a potent and selective JAK2 JH2 binder, with a Kd of 37.1 nM. JAK2 JH2 binder-1 has the potential for various myeloproliferative neoplasms research[1].
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/jak2-jh2-binder-1.html
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: NC1=NC(NC2=CC=C(C=C2)S(=O)(N)=O)=NN1C(NC3=CC=C(C=C3)C4=CC(C(O)=O)=C(C=C4)OCC5=CC=CC=C5)=O
- Molecular Weight: 599.62
- References & Citations: [1]Losi ME, et, al. Insights on JAK2 Modulation by Potent, Selective, and Cell-Permeable Pseudokinase-Domain Ligands. J Med Chem. 2022 Jun 23;65(12):8380-8400.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported