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DCAF1 binder 1

CAT: 0804-HY-149934-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149934-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DCAF1 binder 1 is a selective for the CRL4 DCAF1 E3 ligase complex. DCAF1 binder 1 is a ligands for E3 Ligase, involving in targeted protein degradation (TPD) [1].
CAS Number
3053860-67-3
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dcaf1-binder-1.html
Purity
99.12
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
NCCNC1=NC(C2(C3=CC=C(C=C3)Cl)CCCCC2)=NC4=C1C=CC(N5CCN(CC5)C(C)=O)=C4
Molecular Formula
C28H35ClN6O
Molecular Weight
507.07
References & Citations
[1]Schroeder M, et al. Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings[J]. bioRxiv, 2023: 2023.04. 09.536153.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon