PSMA binder-1

• Description :

  PSMA binder-1 is a ligand for PSMA and can be used to synthesize PSMA targeting molecule, such as Ac-PSMA-trillium[1][2].

• UNSPSC :

  12352005

• Target :

  PSMA

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/psma-binder-1.html

• Concentration :

  10mM

• Purity :

  98.33

• Solubility :

  DMSO : 30 mg/mL (ultrasonic)

• Smiles :

  C#CC1=CC=CC(NC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=C1

• Molecular Formula :

  C21H26N4O8

• Molecular Weight :

  462.45

• References & Citations :

  [1]Sun M, et al. Prostate-Specific Membrane Antigen (PSMA) -Targeted Radionuclide Therapies for Prostate Cancer. Curr Oncol Rep. 2021 Mar 29;23 (5) :59.|[2]Zitzmann-Kolbe S, et al., Preclinical evaluation of an actinium-225 labeled PSMA-targeting small molecule (225Ac-PSMA-Trillium (BAY 3563254) ) for the treatment of metastatic castration resistant prostate cancer (mCRPC) [J]. Cancer Research, 2024, 84 (6_Supplement) : 6033-6033.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2170653-14-0]