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AChE-IN-28

CAT: 0804-HY-151927Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151927Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AChE-IN-28 (Compound 2h) is a selective slow-binding inhibitor of acetylcholinesterase with an IC50 of 0.2 nM[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-28.html
Solubility
10 mM in DMSO
Smiles
CC[N+](CCCCCN1C(C=CN(C1=O)CCCCCCN(C(C=C2=O)C)C(N2C)=O)=O)(CC3=CC=CC=C3C(F)(F)F)CC.[Br-]
Molecular Formula
C33H48BrF3N5O4
Molecular Weight
715.66
References & Citations
[1]Saifina LF, et al. Novel slow-binding reversible acetylcholinesterase inhibitors based on uracil moieties for possible treatment of myasthenia gravis and protection from organophosphate poisoning. Eur J Med Chem. 2022 Nov 24;246:114949.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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