HDAC6-IN-14
CAT:
804-HY-151896
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HDAC6-IN-14
- CAS Number: 3023019-97-5
- UNSPSC Description: HDAC6-IN-14 is a highly selective HDAC6 (HDAC) inhibitor with an IC50 of 42 nM. HDAC6-IN-14 displays >100-fold selectivity over HDAC1/HDAC2/HDAC3/HDAC4[1].
- Target Antigen: HDAC
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hdac6-in-14.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NO)C1=CC=C(CN(CC(NC(C)(C)C)=O)C(C2=CC=CC=C2C(C)C)=O)C(F)=C1
- Molecular Weight: 443.51
- References & Citations: [1]Nina Reßing, et al. Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute Leukemia. J Med Chem. 2022 Nov 24;65(22):15457-15472.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported