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HDAC6-IN-11

CAT: 0804-HY-150694Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150694Size:1 Each
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Description
HDAC6-IN-11 (Compound 9) is a selective HDAC6 inhibitor with the IC50 value of 20.7 nM. HDAC6-IN-11 has more than 300-fold selectivity over HDAC other isoforms. HDAC6-IN-11 shows anti-proliferative activities against cancer cells[1].
CAS Number
2409072-27-9
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac6-in-11.html
Solubility
10 mM in DMSO
Smiles
O=C(NO)/C=C/C1=NC2=CC=C(OC3=CC=C(OC)C=C3)C=C2C=C1
Molecular Formula
C19H16N2O4
Molecular Weight
336.34
References & Citations
[1]Shih-Wei Wang, et al. Synthesis and biological evaluation of 2-quinolineacrylamides. Bioorg Med Chem. 2020 Feb 1;28 (3) :115250.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC6; HDAC8

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