HDAC6-IN-8
CAT:
804-HY-147730
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HDAC6-IN-8
- CAS Number: 2796282-49-8
- UNSPSC Description: A variety of compounds were designed and synthesized by modifying cap groups. The enzyme inhibition test showed that compound 12C had broad-spectrum enzyme inhibitory activity, and compounds 9m and 9q were more inclined to inhibit HDAC6, showing a certain selective inhibitory activity among the representative subtypes.
- Target Antigen: HDAC
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hdac6-in-8.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=CC=C2N=CN=C(C2=C1)NC3=CC(F)=C(C=C3)Br)CC4=CC=C(C=C4)C(NO)=O
- Molecular Weight: 510.32
- References & Citations: [1]Li X,et al. Design, Synthesis, and biological evaluation of HDAC6 inhibitors based on Cap modification strategy. Bioorg Chem. 2022 May 24;125:105874.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported