HDAC6-IN-66

• Description :

  HDAC6-IN-66 is a potent and selective histone deacetylase (HDAC) 6 inhibitor with an IC50 of 1.8 nM. HDAC6-IN-66 induces α-tubulin acetylation over histone H3. HDAC6-IN-66 can be used for the research of cancer[1].

• UNSPSC :

  12352005

• Target :

  HDAC

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  O=C(NO)C1=CC=C(CN2N=C(C3=CC=CO3)C4=C2C=CC=C4)C=C1

• Molecular Formula :

  C19H15N3O3

• Molecular Weight :

  333.34

• References & Citations :

  [1]Ali KH, et al. Design, synthesis, and biological evaluation of indazole-based histone deacetylase 6 inhibitors. Eur J Med Chem. 2025 Oct 5;295:117785.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  HDAC1; HDAC3; HDAC6

• CAS Number :

  [3095060-23-1]