CBR Agonist-2

• Description :

  CBR Agonist-2 is a CB1 agonist (CB1R; CB1 ligand) with an EC50 and a Ki of 960 nM and 970 nM, respectively. CBR Agonist-2 is a promising tool for investigating the involvement of hCB1R in disorders associated with the endocannabinoid system[1].

• UNSPSC :

  12352005

• Target :

  Cannabinoid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cbr-agonist-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CN(C2=CC=CC=C12)CCCCCF)NCC3=CC=CC=C3/N=N/C4=CC=CC=C4

• Molecular Formula :

  C27H27FN4O

• Molecular Weight :

  442.53

• References & Citations :

  [1]Diego A Rodríguez-Soacha, et al. Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB 1 R) "Cis-On" Agonist. ACS Chem Neurosci.2022 Jul 26. doi: 10.1021/acschemneuro.2c00160.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CB1