COX-2-IN-28

• UNSPSC Description:

  COX-2-IN-28 is a potent and selective COX-2 inhibitor with IC50 values of 0.054, 2.14, 13.21 μM for COX-2, 15-LOX, COX-1,respectively[1].

• Target Antigen:

  COX

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cox-2-in-28.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C/C(CNC1=NC(N2C(SC)=NC3=CC=CC=C23)=CS1)=N\N=C4SC=C(C5=CC=C(C)C=C5)N/4C6=CC=CC=C6

• Molecular Weight:

  581.78

• References & Citations:

  [1]Maghraby MT, et al. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes. Bioorg Med Chem. 2020 Apr 1;28(7):115403.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2413565-18-9