PI3K-IN-22

CAT: 0804-HY-10620Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-10620Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3K-IN-22 is a PI3Kα/mTOR dual kinase inhibitor. PI3K-IN-22 has IC50s of 0.9, 0.6 nM for PI3Kα and mTOR, respectively. PI3K-IN-22 can be used for the research of cancer[1].
CAS Number
[1202884-94-3]
UNSPSC
12352005
Target
MTOR; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-in-22.html
Purity
99.50
Solubility
DMSO : 15 mg/mL (ultrasonic; warming)
Smiles
O=C(NC1=CC=C(C(N(C)CCN(C)C)=O)C=C1)NC(C=C2)=CC=C2C3=NC4=C(C=CN4CC(F)(F)F)C(N5CCOCC5)=N3
Molecular Formula
C31H35F3N8O3
Molecular Weight
624.66
References & Citations
[1]Chen Z, et al. Synthesis and SAR of novel 4-morpholinopyrrolopyrimidine derivatives as potent phosphatidylinositol 3-kinase inhibitors. J Med Chem. 2010 Apr 22;53 (8) :3169-82.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MTOR; PI3Kα

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