PI3K-IN-22

PI3K-IN-22

• CAS Number: 1202884-94-3
• UNSPSC Description: PI3K-IN-22 is a PI3Kα/mTOR dual kinase inhibitor. PI3K-IN-22 has IC50s of 0.9, 0.6 nM for PI3Kα and mTOR, respectively. PI3K-IN-22 can be used for the research of cancer[1].
• Target Antigen: mTOR; PI3K
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3k-in-22.html
• Purity: 99.50
• Solubility: DMSO : 15 mg/mL (ultrasonic;warming)
• Smiles: O=C(NC1=CC=C(C(N(C)CCN(C)C)=O)C=C1)NC(C=C2)=CC=C2C3=NC4=C(C=CN4CC(F)(F)F)C(N5CCOCC5)=N3
• Molecular Weight: 624.66
• References & Citations: [1]Chen Z, et al. Synthesis and SAR of novel 4-morpholinopyrrolopyrimidine derivatives as potent phosphatidylinositol 3-kinase inhibitors. J Med Chem. 2010 Apr 22;53(8):3169-82.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported