MAT2A-IN-7

• UNSPSC Description:

  MAT2A-IN-7 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-7 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-7 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 24)[1].

• Target Antigen:

  Methionine Adenosyltransferase (MAT)

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mat2a-in-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(C2=CC=CC=C2Cl)C3=C(C=CC(C(F)(F)F)=N3)C(NC)=C1OC

• Molecular Weight:

  383.75

• References & Citations:

  [1]Li Zhen, et al. Bicyclic compounds. Patent WO2021254529A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2756458-77-0