MAT2A-IN-7

MAT2A-IN-7

• CAS Number: 2756458-77-0
• UNSPSC Description: MAT2A-IN-7 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-7 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-7 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 24)[1].
• Target Antigen: Methionine Adenosyltransferase (MAT)
• Type: Reference compound
• Related Pathways: Epigenetics;Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mat2a-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N(C2=CC=CC=C2Cl)C3=C(C=CC(C(F)(F)F)=N3)C(NC)=C1OC
• Molecular Weight: 383.75
• References & Citations: [1]Li Zhen, et al. Bicyclic compounds. Patent WO2021254529A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported