β-catenin-IN-7

β-catenin-IN-7

• CAS Number: 2952779-17-6
• UNSPSC Description: β-catenin-IN-7 (Compound 9) is a β-catenin inhibitor. β-catenin-IN-7 inhibits the interaction between β-catenin and Tcf-4, and inhibits Wnt-dependent target gene expression. β-catenin-IN-7 has anti-cancer activity[1].
• Target Antigen: Wnt
• Type: Reference compound
• Related Pathways: Stem Cell/Wnt
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/β-catenin-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: O=S(C1=CC=C(Br)C=C1)(NC2=CC=C(C3=NC=CC=C3)C=C2)=O
• Molecular Weight: 389.27
• References & Citations: [1]Nalli M, et al. Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent. ACS Pharmacol Transl Sci. 2023 Jul 3;6(7):1087-1103.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported