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β-catenin-IN-9

CAT: 0804-HY-179408Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179408Size:1 Each
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Description
β-catenin-IN-9 is a β-catenin inhibitor. β-catenin-IN-9 induces apoptosis, cell cycle arrest, and inhibits migration, invasion, and epithelial-mesenchymal transition (EMT) in colorectal cancer cells. β-catenin-IN-9 suppresses the transcription of β-catenin and vimentin, and significantly inhibits β-catenin at the protein level. β-catenin-IN-9 can be used for the research of colorectal cancer[1].
CAS Number
3029462-00-5
UNSPSC
12352005
Target
Apoptosis; β-catenin
Related Pathways
Apoptosis; Stem Cell/Wnt
Field of Research
Cancer
Smiles
CCCCCCCCCCCCCCCCCC1=NN=C(SCN2CCOCC2)N1/N=C/C3=CN(CC4=CC=CC=C4)C5=C3C=CC=C5
Molecular Formula
C40H58N6OS
Molecular Weight
670.99
References & Citations
[1]Abdelmegeed H, et al. A novel 1,2,4-triazole derivative inhibits epithelial-mesenchymal transition in metastatic colorectal cancer via β-catenin suppression. Eur J Med Chem. 2026;302 (Pt 1) :118279.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported