β-catenin-IN-37
CAT:
804-HY-115543-01
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
β-catenin-IN-37
- Alternative Name: CP 526555 (dihydrochloride)
- CAS Number: 1783856-40-5
- UNSPSC Description: β-catenin-IN-37 is a selective β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) inhibitor. β-catenin-IN-37 inhibits canonical Wnt signaling and the growth of colorectal cancer cells SW480 and HCT116 with the IC50 values of 20 μM and 31 μM, respectively[1].
- Target Antigen: β-catenin
- Type: Reference compound
- Related Pathways: Stem Cell/Wnt
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/β-catenin-in-37.html
- Purity: 99.13
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: N1(CCC2=NNN=N2)C3=NC4=NON=C4N=C3C5=C1C=CC=C5
- Molecular Weight: 307.27
- References & Citations: [1]Catrow JL, et al. Discovery of Selective Small-Molecule Inhibitors for the β-Catenin/T-Cell Factor Protein-Protein Interaction through the Optimization of the Acyl Hydrazone Moiety. J Med Chem. 2015;58(11):4678-4692.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported