β-catenin-IN-8
CAT:
804-HY-169348
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
β-catenin-IN-8
- CAS Number: 259130-14-8
- UNSPSC Description: β-catenin-IN-8 (Compound 25) is a β-catenin inhibitor. β-catenin-IN-8 inhibits β-catenin and c-Myc protein levels, and inhibits Wnt-target genes level (Fgf20 and Sall4). β-catenin-IN-8 has colorectal cancer anticancer activities, and has metabolic stability[1].
- Target Antigen: c-Myc; Wnt; β-catenin
- Type: Reference compound
- Related Pathways: Apoptosis;Stem Cell/Wnt
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/β-catenin-in-8.html
- Smiles: O=S(C1=CC=C(Cl)C=C1)(NC2=CC=C(N3C=CN=C3)C=C2)=O
- Molecular Weight: 333.79
- References & Citations: [1]Puxeddu M, et al. Development of N-(4-(1H-Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability. J Med Chem. 2024 Nov 28;67(22):20298-20314.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported