β-Catenin modulator-7

• CAS Number :

  2892294-93-6

• Bioactivity :

  ?-Cateninmodulator-7 (Compound 5) acts as a regulator of ?-catenin. It suppresses the expression of ?-catenin in both the cytoplasm and nucleus of HCT-116 cells and inhibits the phosphorylation of GSK 3?. Additionally, ?-Cateninmodulator-7 facilitates the release of NO in HCT-116 cells and inhibits the proliferation of these cancer cells, with an IC50 value of 0.6-0.9 ?M. This compound is utilized in research related to colon cancer.

• Smiles :

  O=C(OCON=N(=O)N(CC)CC)CCCCOC1=C(OC)C=C(C=CC(=O)N2C(=O)C(Cl)=CCC2)C=C1OC

• Molecular Formula :

  C26H35ClN4O9

• Molecular Weight :

  583.03

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C