CTL-06

CAT: 0804-HY-149540Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149540Size:1 Each
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Description
CTL-06 is an inhibitor of Fatty Acid Synthase (FASN) (IC50: 3 μM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research[1].
UNSPSC
12352005
Target
Fatty Acid Synthase (FASN)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ctl-06.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C2C(N=C(C3=C(O)C=CC(Cl)=C3)N2)=C1)N4CCN(C(OCC)=O)CC4
Molecular Formula
C21H21ClN4O4
Molecular Weight
428.87
References & Citations
[1]Singh S, et al. Design, synthesis, and anticancer activity of some novel 1H-benzo [d] imidazole-5-carboxamide derivatives as fatty acid synthase inhibitors[J]. Bioorganic Chemistry, 2023: 106658.. . .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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