CTL-06

CAT: 804-HY-149540Size: 1 EachDry Ice: NoHazardous: No

1 EachSelected

PRICE

AVAILABILITY

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

CTL-06 is an inhibitor of Fatty Acid Synthase (FASN) (IC50: 3 μM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research[1].

UNSPSC

12352005

Target

Fatty Acid Synthase (FASN)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ctl-06.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C2C(N=C(C3=C(O)C=CC(Cl)=C3)N2)=C1)N4CCN(C(OCC)=O)CC4

Molecular Formula

C21H21ClN4O4

Molecular Weight

428.87

References & Citations

[1]Singh S, et al. Design, synthesis, and anticancer activity of some novel 1H-benzo [d] imidazole-5-carboxamide derivatives as fatty acid synthase inhibitors[J]. Bioorganic Chemistry, 2023: 106658.. . .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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CTL-06

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